HER2 Low Breast Cancer: What Are the Latest Advancements in Novel Drug Antibody Conjugates for 2023? Yuan Yuan, MD - Synopsis below extracted from the video transcript
Recent developments in our profession, including antibody drug conjugates notably Trastuzumab Deruxtecan, a monoclonal antibody in HER2 low illness, have significantly altered our perception of breast cancer. We previously classified breast cancer as triple-negative, HER2-positive, and ER positive. Now the HER2 low has eliminated the old barrier and put them into the non-HER2 low category, which is really exciting.
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The data is really encouraging. In addition to the most recent FDA clearance of Sacituzumab Govitecan for the treatment of HR-positive, HER2-negative cancers. Additionally provides more choices for home-receptor-positive patients who have to transition to chemotherapy. They now have other choices. I believe the greatest difficulty or future difficulty will be determining how to sequence the agents.
